Health & Beauty

Why One in Three Depression Patients Never Respond to Standard Antidepressants

Feeling like nothing has worked is a common experience among people with treatment-resistant depression, but it is not the same thing as having exhausted the actual options. The category exists precisely because the standard sequence of oral antidepressants does not work for everyone, and the treatments developed specifically for this population, including esketamine, exist because researchers recognized that gap and built something to address it directly.